Let's share our community's commitment to honor and support the many people impacted by IPF.
Visit the Esbriet® (pirfenidone) booth at this year's Pulmonary Fibrosis Foundation (PFF) Summit, November 12-14, 2015.

Preserving your lung function is essential—and Esbriet may help

Although lung function (how well the lungs work) cannot be restored, treatment may help maintain more of your lung function and slow the progression of disease.

Esbriet may help preserve more of your lung function

At the end of a 1-year clinical study of people with IPF, more people who took Esbriet had stable lung function, compared with people who did not take Esbriet.

With Esbriet, 23% of people had stable lung function

Without Esbriet, 10% of people had stable lung function

One of the two 72-week trials also showed that more patients taking Esbriet had no decline in lung function, compared with patients who did not take Esbriet. The other 72-week trial did not show a significant difference between patients who took Esbriet and those who did not.

What are the possible side effects of Esbriet?

Some people may have serious side effects when taking Esbriet, including liver problems, sensitivity to sunlight (including sunlamps), or stomach problems. Other reported side effects that occurred in 10% or more of people treated with Esbriet in clinical studies included feeling tired, headache, dizziness, and a decreased or loss of appetite. In the clinical studies for Esbriet, some side effects occurred soon after starting treatment, but decreased over time.

These are not all of the side effects reported with Esbriet. See Important Safety Information below to learn more about possible side effects of Esbriet.

How to manage and prevent certain side effects

Be sure to discuss any side effects and how to manage them with your doctor. Here are some important ways to help manage and prevent specific side effects.

Nausea and dizziness

Always take Esbriet with food. Taking Esbriet during your meals may reduce nausea and dizziness.

Preventing skin rash and sun sensitivity

Always use a broad-spectrum (UVA/UVB) sunscreen with SPF 50 or higher when outside. Reapply often throughout the day.

Protect your face by wearing a hat. Wear clothing that covers your skin, including your arms and legs.

Learn more about treating IPF with Esbriet

Esbriet Inspiration Program
Sign up for more information about Esbriet, financial assistance, and resources.
Call our 24/7 Nurse Support
Line at (844) 693-7274
(844) MY-ESBRIET

For help with financial
support, visit Esbriet Access Solutions or call (844) ESBRIET (844) 372-7438

Visit the Esbriet® (pirfenidone) booth at the Pulmonary Fibrosis Foundation Summit 2015

Join us at the booth

Take the I Preserve For pledge and share your IPF motivation

  • Learn more about how Esbriet can help treat idiopathic pulmonary fibrosis (IPF).
  • Share your journey with the community

Can't stop by the Summit?

  • Join the IPF conversation on social media #IPreserveFor
  • Learn more about how Esbriet can help treat idiopathic pulmonary fibrosis (IPF).

The PFF Summit is an educational and collaborative event to support the IPF community. Over the 3-day Summit, patients, caregivers, and healthcare professionals share the latest information in more than 50 sessions and activities. This year the Summit is being held at hte JW Marriott Washington, D.C.

Indication and Select Important Safety Information

About Esbriet

Esbriet® (pirfenidone) is a prescription medicine used to treat people with a lung disease called idiopathic pulmonary fibrosis (IPF).

Select Important Safety Information
 

What should I tell my doctor before taking Esbriet?

Before you take Esbriet, tell your doctor if you:

  • have liver problems
  • have kidney problems
  • are a smoker
  • have any other medical condidtions
  • are pregnant or plan to become pregnant. It is not known if Esbriet will harm your unborn baby.
  • are breastfeeding of plan to breastfeed. It is not known if Esbriet passes into your breast milk. You and your doctor should decide if you will take Esbriet or breastfeed.

What should I avoid while taking Esbriet?

  • Avoid sunlight. Esbriet can make your skin sensitive to the sun and the light from sunlamps and tanning beds. You could get a severe sunburn. Use sunscreen (SPF 50) and wear a hat and clothes that cover your skin if you have to be in sunlight. Talk to your doctor if you get sunburn..
  • Avoid smoking. Smoking may affect how well Esbriet works.

What are the possible side effects of Esbriet?

Esbriet may cause serious side effects, including:

  • liver problems. Call your doctor right away if you have unexplained symptoms such as yellowing of your skin or the white part of your eyes (jaundice), dark or brown (tea-colored) urine, pain on the upper right side of your stomach area (abdomen), bleeding or bruising more easily than normal, or feeling tired. Your doctor will do blood tests to check how your liver is working during your treatment with Esbriet..
  • sensitivity to sunlight (photosensitivity) and rash. See "What should I avoid while taking Esbriet?"
  • stomach problems. Esbriet may cause stomach problems such as nausea, vomiting, diarrhea, indigestion, heartburn, and stomach pain. Tell your doctor right away if your stomach problems get worse or do not go away. Your doctor may need to change your dose of Esbriet.
The most common side effects of Esbriet include feeling tired, headache, dizziness, and decreased or loss of appetite.

These are not all the possible side effects of Esbriet. For more information, ask your doctor or pharmacist.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088 or www.fda.gov/medwatch. You may also report side effects to Genentech at 1-888-835-2555.

Please see the full Prescribing Information for additional important safety information.